Opportunity Information: Apply for RFA NR 20 002
Strengthening the Impact of Community Health Workers on the HIV Care Continuum in the US (R01 Clinical Trial Optional) is a National Institutes of Health (NIH) research funding opportunity (RFA NR 20 002; CFDA 93.361) focused on improving HIV outcomes in the United States by building stronger, more effective community health worker (CHW) approaches. The central goal is to fund studies that test how CHWs can better support people living with HIV (PLH) across key steps of the HIV care continuum. In practical terms, NIH is looking for research that evaluates scalable tools, training models, and implementation strategies that enhance CHWs ability to help patients get linked to care, stay engaged in care, take antiretroviral therapy consistently, and ultimately achieve or maintain viral suppression.
A defining requirement of this opportunity is that applications must include at least one patient outcome tied directly to the HIV care continuum. Examples highlighted in the announcement include care engagement, antiretroviral adherence, and viral suppression, but the overall intent is broader: proposed work should measure meaningful, patient-level progress in HIV care that can be attributed to strengthened CHW support. The funding announcement also encourages effectiveness research that goes beyond asking whether CHW interventions work and instead clarifies how and why they work. That means studies that identify mediators and mechanisms of impact (for instance, improved trust in care teams, reduced stigma, better navigation of social services, improved appointment attendance, or stronger self-management skills) are explicitly welcomed. Cost-effectiveness analyses are also encouraged, reflecting an interest in interventions that can be sustained and scaled in real-world settings, not just demonstrated under ideal research conditions.
The mechanism is an NIH R01 grant with clinical trials listed as optional, which signals flexibility in study design. Applicants can propose rigorously designed observational or interventional studies, including clinical trials when appropriate, as long as the work is centered on strengthening CHW capacity and demonstrating measurable improvements in HIV care outcomes. The emphasis on scalable tools and training suggests NIH is prioritizing approaches that can be adopted by health systems, community-based organizations, and public health programs at larger scale, rather than highly specialized models that are difficult to replicate.
Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, city or township governments, special district governments, and independent school districts, as well as public and state-controlled institutions of higher education and private institutions of higher education. Tribal entities are eligible, including federally recognized Native American tribal governments and tribal organizations other than federally recognized tribal governments. The opportunity is also open to public housing authorities/Indian housing authorities, nonprofits with or without 501(c)(3) status (other than institutions of higher education), for-profit organizations other than small businesses, and small businesses. The announcement also highlights additional eligible applicant categories such as faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), along with U.S. territories or possessions and eligible federal agencies.
At the same time, the opportunity places strict limits on foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are not eligible. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed. In other words, the work must be grounded in U.S.-based organizations and settings, consistent with the program focus on improving the HIV care continuum within the United States.
From the provided source details, the opportunity was posted on March 3, 2020, with an original closing date of May 13, 2020. The listed award ceiling is $500,000, indicating the maximum award amount expected per award under this announcement. The number of expected awards is not specified in the provided extract. Overall, the grant is designed to generate actionable evidence on how to better equip and deploy community health workers to improve HIV outcomes, while also building understanding of the pathways through which CHWs produce impact and whether the benefits justify the costs for broader adoption.Apply for RFA NR 20 002
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Strengthening the Impact of Community Health Workers on the HIV Care Continuum in the US (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361.
- This funding opportunity was created on 2020-03-03.
- Applicants must submit their applications by 2020-05-13. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the name of this NIH funding opportunity?
The opportunity is titled Strengthening the Impact of Community Health Workers on the HIV Care Continuum in the US (R01 Clinical Trial Optional).
Which agency is offering this grant?
This is a National Institutes of Health (NIH) research funding opportunity.
What are the opportunity identifiers listed?
The announcement lists RFA NR 20 002 and CFDA 93.361.
What is the main purpose of this grant?
The main purpose is to fund research that strengthens community health worker (CHW) approaches to improve HIV outcomes in the United States, specifically by supporting people living with HIV (PLH) across key steps of the HIV care continuum.
What does "HIV care continuum" mean in the context of this opportunity?
In this opportunity, the HIV care continuum refers to patient progress through critical HIV care steps such as getting linked to care, staying engaged in care, taking antiretroviral therapy (ART) consistently, and achieving or maintaining viral suppression.
What types of outcomes does NIH expect applications to measure?
Applications must include at least one patient outcome directly tied to the HIV care continuum. Examples mentioned include care engagement, antiretroviral adherence, and viral suppression. The intent is to measure meaningful patient-level progress in HIV care that can be attributed to strengthened CHW support.
Is at least one HIV care continuum patient outcome required?
Yes. A defining requirement is that the application includes at least one patient outcome tied directly to the HIV care continuum.
What kinds of research approaches are being sought?
NIH is looking for studies that test how CHWs can better support PLH across the HIV care continuum, including research that evaluates scalable tools, training models, and implementation strategies that enhance CHW capacity to improve measurable HIV care outcomes.
Are clinical trials required?
No. The mechanism is an NIH R01 with clinical trials optional, indicating that clinical trials may be included when appropriate, but are not required.
What study designs are allowed under "clinical trial optional"?
The announcement indicates flexibility in study design, allowing rigorously designed observational or interventional studies, including clinical trials when appropriate, as long as the work centers on strengthening CHW capacity and demonstrates measurable improvements in HIV care outcomes.
What does NIH mean by "scalable" CHW approaches?
Based on the announcement, "scalable" approaches include tools, training models, and implementation strategies that can be adopted by health systems, community-based organizations, and public health programs at larger scale, rather than highly specialized models that are difficult to replicate.
Does the opportunity encourage research on how and why CHW interventions work?
Yes. The announcement encourages effectiveness research that goes beyond whether CHW interventions work and instead clarifies how and why they work, including identifying mediators and mechanisms of impact.
What are examples of mechanisms or mediators of impact mentioned?
Examples highlighted include improved trust in care teams, reduced stigma, better navigation of social services, improved appointment attendance, and stronger self-management skills.
Are cost-effectiveness analyses encouraged?
Yes. Cost-effectiveness analyses are explicitly encouraged, reflecting interest in interventions that can be sustained and scaled in real-world settings.
What grant mechanism is being used?
The funding mechanism is an NIH R01 research grant.
What is the geographic focus of the funded work?
The work must focus on improving the HIV care continuum within the United States, consistent with the opportunity's stated focus.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and government entities, including state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; and a range of other eligible entities described in the announcement.
Are tribal entities eligible to apply?
Yes. Eligible applicants include federally recognized Native American tribal governments and tribal organizations other than federally recognized tribal governments.
Can nonprofits apply?
Yes. The opportunity is open to nonprofits with or without 501(c)(3) status (other than institutions of higher education).
Can for-profit organizations apply?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.
Are community-based and faith-based organizations included as eligible applicants?
Yes. The announcement highlights additional eligible applicant categories, including faith-based or community-based organizations.
Are minority-serving institutions specifically called out as eligible?
Yes. The announcement highlights eligibility for Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs).
Are U.S. territories or possessions eligible?
Yes. The announcement includes U.S. territories or possessions among the eligible applicant categories.
Are federal agencies eligible to apply?
Yes. The announcement includes eligible federal agencies among the eligible applicant categories.
Are non-U.S. (foreign) organizations eligible to apply?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply.
Can a U.S. organization include a non-domestic component in the project?
No. Non-domestic components of U.S. organizations are not eligible under this opportunity.
Are foreign components allowed in any form?
No. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed. The work must be grounded in U.S.-based organizations and settings.
When was this opportunity posted?
The opportunity was posted on March 3, 2020.
What was the original closing date listed?
The original closing date listed is May 13, 2020.
What is the maximum award amount (award ceiling)?
The listed award ceiling is $500,000, indicating the maximum award amount expected per award under this announcement.
How many awards does NIH expect to make?
The number of expected awards is not specified in the provided details.
What kinds of CHW supports or enhancements are especially aligned with this opportunity?
The announcement emphasizes research that strengthens CHW approaches through scalable tools, training models, and implementation strategies that improve CHWs ability to help patients link to care, remain in care, adhere to ART, and achieve or maintain viral suppression.
Does the opportunity prioritize real-world sustainability and adoption?
Yes. The focus on scalability and the encouragement of cost-effectiveness analysis reflect an interest in approaches that can be sustained and adopted in real-world settings, not only proven under ideal research conditions.
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