Opportunity Information: Apply for CDC RFA GH 23 0006
This funding opportunity, titled "Provision of Voluntary Medical Male Circumcision (VMMC) for HIV Prevention in the Republic of South Africa under PEPFAR," is a CDC cooperative agreement (Funding Opportunity Number CDC RFA GH 23 0006) intended to strengthen and accelerate South Africa's scale-up of voluntary medical male circumcision as a proven HIV prevention intervention. It sits under the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Center for Global Health, and is listed under CFDA 93.067 in the health funding activity category. Applications were due March 7, 2023 (11:59 pm ET), and the program anticipated making about five awards. Eligibility is described as unrestricted, meaning a wide range of entity types could apply, as long as they meet any additional eligibility details specified in the full announcement.
The notice outlines an unusual but important funding detail: the "Award Ceiling for Year 1" is listed as 0 (none), which typically signals that a maximum cap per award is not being set in the announcement for that budget period rather than indicating no funding will be provided. At the same time, CDC projected an approximate total funding amount of $50,000,000 for Year 1, explicitly subject to the availability of funds. In practice, this means applicants should expect CDC to fund a portfolio of awards that together may total around that amount, while the final figures could shift based on appropriations, program priorities, and award negotiations.
Programmatically, the goal is to support the South African Government (SAG) to expand VMMC services across 27 districts with high HIV burden, with extra emphasis on geographic areas where male circumcision coverage is low. The intended public health outcome is to help South Africa rapidly reach an 80 percent VMMC coverage level among males ages 15 to 29, a priority age band because increasing circumcision coverage in this group can have a meaningful impact on reducing new HIV infections at the population level over time. The award is framed as support to government scale-up rather than a stand-alone implementing project, and recipients are expected to coordinate closely with CDC, SAG counterparts, PEPFAR-supported implementing partners, and other stakeholders involved in VMMC programming.
The required approach combines demand generation with high-quality, efficient service delivery. On the demand side, recipients are expected to implement effective and innovative strategies that increase acceptance and uptake of VMMC, which can include targeted outreach in priority communities, age-appropriate messaging for adolescents and young men, and interventions designed to address common barriers such as fear of pain, time off work or school, misinformation, stigma, or concerns about confidentiality. The intention is not just to advertise services, but to create informed demand that translates into completed circumcisions and appropriate follow-up care.
On the service delivery side, the opportunity emphasizes evidence-based modalities that support high-volume, cost-efficient VMMC while maintaining safety and quality. That typically implies optimizing service models (for example, fixed sites, outreach, and integrated service points), improving client flow and scheduling, ensuring adherence to clinical standards, and using approaches that reduce bottlenecks without compromising infection prevention, surgical safety, or client experience. Because VMMC is part of a broader HIV prevention strategy, the announcement also expects recipients to support implementation and integration of VMMC within comprehensive HIV prevention, care, and treatment services. In real terms, this integration often means strengthening HIV testing services and linkage pathways, providing prevention counseling, supporting STI screening and management where appropriate, promoting condoms and risk-reduction education, and connecting clients to other relevant health services.
A major component is workforce development and clinical quality. Recipients are expected to build the capacity of VMMC service delivery personnel through training, mentoring, skills-building, and continuing education. This points to ongoing competency-based support for providers, supervisors, and program managers, including maintaining clinical proficiency, strengthening supportive supervision, standardizing best practices, and ensuring that quality improvement is continuous rather than limited to one-off trainings. The emphasis on quality is reinforced by explicit references to quality assurance, which generally includes clinical audits, adverse event monitoring and reporting, adherence to national guidelines, and routine use of data to identify and correct performance gaps.
The NOFO also highlights supply chain and commodity management as a core responsibility. Recipients are expected to strengthen forecasting, procurement, quality assurance, storage, and distribution for VMMC surgical kits and other related commodities. This is critical because VMMC programs can be disrupted by stock-outs, poor distribution planning, inadequate storage conditions, or inconsistent kit quality. Strong forecasting and logistics are needed to match supply to demand across multiple districts, especially when campaigns or seasonal peaks cause rapid surges in service volume.
Finally, the award places clear weight on sustainability and transition to government systems. Recipients must provide technical assistance to support the transition, integration, and monitoring of direct VMMC services to the South African Department of Health and to public health facilities. The practical aim is to reduce long-term dependence on external implementing structures by embedding VMMC delivery and oversight into routine government health services, strengthening government-led monitoring and performance management, and ensuring public facilities can plan, deliver, and track VMMC services effectively over time. In short, the opportunity is designed to accelerate coverage gains in priority districts while building lasting capacity in South Africa's public health system to manage and sustain VMMC as a central HIV prevention intervention under PEPFAR.Apply for CDC RFA GH 23 0006
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Provision of Voluntary Medical Male Circumcision (VMMC) for HIV Prevention in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Jan 06, 2023.
- Applicants must submit their applications by Mar 07, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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