Opportunity Information: Apply for RFA HG 20 019

The NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed) funding opportunity, RFA-HG-20-019, is a National Institutes of Health (NIH) cooperative agreement intended to create a single Coordinating Center that strengthens and connects the different parts of the National Human Genome Research Institute (NHGRI) Genome Technology program. The overall aim is not to run clinical trials, but to accelerate progress in genome technology by improving coordination, collaboration, standards development, and communication across the program and out to the broader research community. As a U24 cooperative agreement, recipients should expect substantial involvement from NIH/NHGRI staff in shaping priorities, coordinating activities, and ensuring the Center functions as an integrated hub for the program.

The Coordinating Center is expected to play several core roles. First, it should enhance integration among the various NHGRI Genome Technology program components by actively facilitating collaboration opportunities. In practical terms, this means serving as a central organizer and connector across funded groups, helping investigators find partners, align complementary expertise, reduce duplication of effort, and move promising methods forward more efficiently. Second, the Center is tasked with leading efforts to promote standards in genomic technologies. That typically involves encouraging common technical benchmarks, shared data formats, interoperable tools, best practices, and other standardization activities that help technologies be compared, validated, adopted, and scaled across labs and platforms.

Another major responsibility is dissemination and outreach. The Center should communicate program advances and make them easier to find, understand, and reuse by the broader biomedical research community. This can include developing and maintaining resources such as websites, knowledge bases, newsletters, workshops, webinars, documentation, and other outreach strategies tailored to scientists, tool developers, and related stakeholders. The intent is to ensure that innovations coming out of the NHGRI Genome Technology program do not remain siloed within funded teams, but instead are broadly visible and positioned for uptake.

A distinctive feature of this opportunity is the requirement to manage an Opportunity Funds program. The Coordinating Center would administer a rapid, small-scale funding mechanism designed to quickly support high-potential, targeted work that advances innovative genomic technologies. The purpose of this internal funding pool is speed and flexibility: it can be used to seed early experiments, bridge gaps, support time-sensitive proof-of-concept efforts, or enable short, focused collaborations that may not fit neatly into longer standard grant cycles. The Center is therefore expected to develop fair and efficient processes for soliciting ideas, reviewing proposals, selecting projects, tracking progress, and reporting outcomes, while keeping administrative overhead low and maintaining transparency and accountability.

From an administrative perspective, this FOA is categorized as discretionary funding, with a health-related activity focus under CFDA 93.172. The listing indicates an expected number of awards of one, meaning NHGRI anticipated funding a single Coordinating Center to serve the entire program. The award ceiling is shown as 0, which typically signals that the maximum budget is not provided in that specific data field and applicants would need to consult the full FOA text for detailed budget guidance, cost expectations, and any constraints. The opportunity was posted March 12, 2020, with an original closing date of June 24, 2020.

Eligibility is broad and includes many types of organizations, such as state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (outside of higher education); for-profit organizations other than small businesses; small businesses; and other entities as described in the FOA’s additional eligibility language. This wide eligibility suggests NHGRI was primarily focused on finding the strongest coordinating entity with the infrastructure and expertise to manage complex program-wide activities, rather than restricting the applicant pool to a narrow institutional type.

In short, this grant opportunity funds a central coordinating organization to knit together NHGRI’s genome technology investments by building connections among projects, promoting shared standards, broadcasting progress and resources, and quickly seeding promising small efforts through an Opportunity Funds mechanism. The emphasis is on program integration and acceleration of technology development, with NIH collaboration built into the award structure and no clinical trials permitted under this FOA.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172.
  • This funding opportunity was created on Mar 12, 2020.
  • Applicants must submit their applications by Jun 24, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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