Opportunity Information: Apply for RFA HG 20 019
The NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed) funding opportunity, RFA-HG-20-019, is a National Institutes of Health (NIH) cooperative agreement intended to create a single Coordinating Center that strengthens and connects the different parts of the National Human Genome Research Institute (NHGRI) Genome Technology program. The overall aim is not to run clinical trials, but to accelerate progress in genome technology by improving coordination, collaboration, standards development, and communication across the program and out to the broader research community. As a U24 cooperative agreement, recipients should expect substantial involvement from NIH/NHGRI staff in shaping priorities, coordinating activities, and ensuring the Center functions as an integrated hub for the program.
The Coordinating Center is expected to play several core roles. First, it should enhance integration among the various NHGRI Genome Technology program components by actively facilitating collaboration opportunities. In practical terms, this means serving as a central organizer and connector across funded groups, helping investigators find partners, align complementary expertise, reduce duplication of effort, and move promising methods forward more efficiently. Second, the Center is tasked with leading efforts to promote standards in genomic technologies. That typically involves encouraging common technical benchmarks, shared data formats, interoperable tools, best practices, and other standardization activities that help technologies be compared, validated, adopted, and scaled across labs and platforms.
Another major responsibility is dissemination and outreach. The Center should communicate program advances and make them easier to find, understand, and reuse by the broader biomedical research community. This can include developing and maintaining resources such as websites, knowledge bases, newsletters, workshops, webinars, documentation, and other outreach strategies tailored to scientists, tool developers, and related stakeholders. The intent is to ensure that innovations coming out of the NHGRI Genome Technology program do not remain siloed within funded teams, but instead are broadly visible and positioned for uptake.
A distinctive feature of this opportunity is the requirement to manage an Opportunity Funds program. The Coordinating Center would administer a rapid, small-scale funding mechanism designed to quickly support high-potential, targeted work that advances innovative genomic technologies. The purpose of this internal funding pool is speed and flexibility: it can be used to seed early experiments, bridge gaps, support time-sensitive proof-of-concept efforts, or enable short, focused collaborations that may not fit neatly into longer standard grant cycles. The Center is therefore expected to develop fair and efficient processes for soliciting ideas, reviewing proposals, selecting projects, tracking progress, and reporting outcomes, while keeping administrative overhead low and maintaining transparency and accountability.
From an administrative perspective, this FOA is categorized as discretionary funding, with a health-related activity focus under CFDA 93.172. The listing indicates an expected number of awards of one, meaning NHGRI anticipated funding a single Coordinating Center to serve the entire program. The award ceiling is shown as 0, which typically signals that the maximum budget is not provided in that specific data field and applicants would need to consult the full FOA text for detailed budget guidance, cost expectations, and any constraints. The opportunity was posted March 12, 2020, with an original closing date of June 24, 2020.
Eligibility is broad and includes many types of organizations, such as state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (outside of higher education); for-profit organizations other than small businesses; small businesses; and other entities as described in the FOA’s additional eligibility language. This wide eligibility suggests NHGRI was primarily focused on finding the strongest coordinating entity with the infrastructure and expertise to manage complex program-wide activities, rather than restricting the applicant pool to a narrow institutional type.
In short, this grant opportunity funds a central coordinating organization to knit together NHGRI’s genome technology investments by building connections among projects, promoting shared standards, broadcasting progress and resources, and quickly seeding promising small efforts through an Opportunity Funds mechanism. The emphasis is on program integration and acceleration of technology development, with NIH collaboration built into the award structure and no clinical trials permitted under this FOA.Apply for RFA HG 20 019
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172.
- This funding opportunity was created on Mar 12, 2020.
- Applicants must submit their applications by Jun 24, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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FAQs: NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed) - RFA-HG-20-019
1) What is RFA-HG-20-019 funding?
RFA-HG-20-019 is a National Institutes of Health (NIH) funding opportunity from the National Human Genome Research Institute (NHGRI) to support a single Technology Development Coordinating Center under a U24 cooperative agreement. The purpose is to strengthen and connect the different parts of the NHGRI Genome Technology program by improving coordination, collaboration, standards development, and communication to the broader research community.
2) What is the main goal of the Coordinating Center?
The main goal is to accelerate progress in genome technology by serving as an integrated hub for the NHGRI Genome Technology program. This includes connecting funded groups, reducing duplication of effort, aligning complementary expertise, promoting standards, and ensuring program outputs are broadly disseminated and easier for the research community to find and reuse.
3) Are clinical trials allowed under this opportunity?
No. This opportunity is explicitly labeled "U24 Clinical Trial Not Allowed," and the overall aim is not to run clinical trials but to advance genome technology through program-level coordination and support activities.
4) What does it mean that this is a U24 cooperative agreement?
A U24 is a cooperative agreement mechanism, which means recipients should expect substantial involvement from NIH/NHGRI staff. NHGRI staff may help shape priorities, coordinate activities, and ensure the Coordinating Center functions as an integrated hub for the program.
5) How many awards were expected?
The listing indicates an expected number of awards of one. NHGRI anticipated funding a single Coordinating Center to serve the entire NHGRI Genome Technology program.
6) What are the core responsibilities of the Coordinating Center?
Based on the description provided, the Coordinating Center is expected to:
- Enhance integration across NHGRI Genome Technology program components by actively facilitating collaboration opportunities.
- Promote standards in genomic technologies (for example, common benchmarks, shared data formats, interoperable tools, and best practices).
- Lead dissemination and outreach so program advances are visible and reusable by the broader biomedical research community.
- Administer an Opportunity Funds program to rapidly support small, targeted, high-potential activities that advance innovative genomic technologies.
7) What kinds of coordination activities are expected?
The Center is intended to serve as a central organizer and connector across funded groups. Practical coordination activities include helping investigators find partners, aligning complementary expertise, reducing duplication of effort, and moving promising methods forward more efficiently across the program.
8) What does "promoting standards" mean in this context?
Promoting standards generally means encouraging approaches that help genomic technologies be compared, validated, adopted, and scaled across laboratories and platforms. Examples mentioned include common technical benchmarks, shared data formats, interoperable tools, and best practices, along with other standardization activities.
9) What dissemination and outreach activities are suggested?
The opportunity describes dissemination and outreach as a major responsibility and notes that the Center may develop and maintain resources such as websites, knowledge bases, newsletters, workshops, webinars, documentation, and other outreach strategies aimed at scientists, tool developers, and related stakeholders.
10) Why is dissemination emphasized?
The intent is to ensure innovations coming out of the NHGRI Genome Technology program do not remain siloed within funded teams. Instead, advances and resources should be broadly visible, easier to find and understand, and positioned for uptake by the wider biomedical research community.
11) What is the Opportunity Funds program?
The Opportunity Funds program is an internal rapid, small-scale funding mechanism that the Coordinating Center is required to manage. It is designed to quickly support high-potential, targeted work that advances innovative genomic technologies.
12) What is the purpose of the Opportunity Funds mechanism?
The purpose is speed and flexibility. The funding can be used to seed early experiments, bridge gaps, support time-sensitive proof-of-concept efforts, or enable short, focused collaborations that may not fit neatly into longer standard grant cycles.
13) What processes must the Coordinating Center put in place for Opportunity Funds?
The Coordinating Center is expected to develop fair and efficient processes for soliciting ideas, reviewing proposals, selecting projects, tracking progress, and reporting outcomes. The description also emphasizes keeping administrative overhead low while maintaining transparency and accountability.
14) What is the CFDA number and program area noted for this opportunity?
The opportunity is associated with CFDA 93.172 and is described as discretionary funding with a health-related activity focus.
15) What does it mean that the award ceiling is shown as "0"?
The award ceiling is shown as 0, which typically indicates that a maximum budget is not provided in that specific data field. Applicants would need to consult the full FOA text for detailed budget guidance, cost expectations, and any constraints.
16) When was the opportunity posted and when did it close?
The opportunity was posted on March 12, 2020, and the original closing date was June 24, 2020.
17) Who is eligible to apply?
Eligibility is broad and includes a wide range of organizations, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and private institutions of higher education
- Federally recognized Native American tribal governments
- Other Native American tribal organizations
- Public housing authorities and Indian housing authorities
- Nonprofits with or without 501(c)(3) status (outside of higher education)
- For-profit organizations other than small businesses
- Small businesses
- Other entities as described in the FOA's additional eligibility language
18) Why is eligibility so broad?
The description indicates NHGRI was likely focused on identifying the strongest coordinating entity with the infrastructure and expertise to manage complex program-wide activities, rather than limiting applications to a narrow institutional category.
19) What is the Coordinating Center expected to connect within NHGRI?
The Center is intended to strengthen and connect different parts of the NHGRI Genome Technology program by improving integration across program components and by facilitating collaboration among funded groups.
20) What is the overall emphasis of this FOA?
The emphasis is on program integration and acceleration of genome technology development, built around coordination, collaboration, standards development, and broad communication, with substantial NIH/NHGRI involvement as part of the cooperative agreement structure and with clinical trials not permitted.
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